Marçal Vilar

Affiliations: 
Instituto de Biomedicina de Valencia SPAIN 
Area:
neurotrophins
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"Marçal Vilar"
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Publications

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Comaposada-Baró R, Benito-Martínez A, Escribano-Saiz JJ, et al. (2023) Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75 signaling in the p75-KO mice. Frontiers in Molecular Neuroscience. 16: 1237458
Franco ML, Nadezhdin KD, Light TP, et al. (2021) Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation. The Journal of Biological Chemistry. 100926
Franco ML, García-Carpio I, Comaposada-Baró R, et al. (2021) TrkA-mediated endocytosis of p75-CTF prevents cholinergic neuron death upon γ-secretase inhibition. Life Science Alliance. 4
Vilar M. (2016) Structural Characterization of the p75 Neurotrophin Receptor: A Stranger in the TNFR Superfamily. Vitamins and Hormones. 104: 57-87
Nadezhdin KD, García-Carpio I, Goncharuk SA, et al. (2016) Structural Basis of p75 Transmembrane Domain Dimerization. The Journal of Biological Chemistry. 291: 12346-57
Vilar M, Sung TC, Chen Z, et al. (2014) Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action. Plos Biology. 12: e1001918
Sung TC, Chen Z, Thuret S, et al. (2013) P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury. Plos One. 8: e69286
Díaz-Moreno M, Hortigüela R, Gonçalves A, et al. (2013) Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice. Neurobiology of Aging. 34: 2623-38
Vilar M, Charalampopoulos I, Kenchappa RS, et al. (2009) Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor. Journal of Cell Science. 122: 3351-7
Vilar M, Charalampopoulos I, Kenchappa RS, et al. (2009) Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron. 62: 72-83
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