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Otto Z. Sellinger

Affiliations: 
Mental Health Research Institute University of Michigan, Ann Arbor, Ann Arbor, MI 
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"Otto Sellinger"
Bio:

Otto Z. Sellinger, research scientist in the Mental Health Research Institute and research scientist in the Department of Psychiatry, Medical School, retired from active faculty status on December 31, 1993, after a productive career in neurochemical research.

Born in Zagreb, Yugoslavia, Dr. Sellinger received his primary education in Rome and his S.B. degree in quantitative biology in 1954 at the Massachusetts Institute of Technology. He received his Ph.D. degree in biochemistry in 1958 at Tulane University, to which he returned as an assistant professor of biochemistry and medicine following two postdoctoral NIH fellowship years in Rome with E. B. Chain (Nobel Laureate, 1945) and in Louvain, Belgium, with C. de Duve (Nobel Laureate, 1974). He came to the University of Michigan in 1965 as an associate research pharmacologist at the Mental Health Research Institute, rising to the rank of research scientist in 1969.

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Parents

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Ernst Boris Chain post-doc (Chemistry Tree)
Christian René De Duve post-doc (Cell Biology Tree)

Children

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Stephen B Tatter research assistant 1979-1982 University of Michigan Medical School Ann Arbor
Raffaele Porta research scientist 1980-1983 University of Naples “Federico II”

Collaborators

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Robert A. Schatz collaborator
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Publications

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de Duve C, Beaufay H, Jacques P, et al. (1989) Intracellular localization of catalase and of some oxidases in rat liver. 1960. Biochimica Et Biophysica Acta. 1000: 321-2
DelBel EA, Padovan AP, Padovan GJ, et al. (1989) Enzymatic inactivation of bradykinin by rat brain neuronal perikarya. Cellular and Molecular Neurobiology. 9: 379-400
Caamaño CA, Azcurra JM, Sellinger OZ, et al. (1989) Kinetics of carboxylmethylation of the charge isoforms of myelin basic protein by protein methyltransferase II. Journal of Neurochemistry. 53: 1883-8
Sellinger OZ, Kramer CM. (1988) The carboxylmethylation of membrane-bound proteins in the aging rat brain. Advances in Experimental Medicine and Biology. 231: 269-80
Sellinger OZ, Kramer CM, Conger A, et al. (1988) The carboxylmethylation of cerebral membrane-bound proteins increases with age. Mechanisms of Ageing and Development. 43: 161-73
Sellinger OZ, Kramer CM, Fischer-Bovenkerk C, et al. (1987) The characterization of a membrane-bound protein carboxylmethylation system in brain. Neurochemistry International. 10: 155-66
Sellinger OZ, Schatz RA, Gregor P. (1986) Cerebral methylations in epileptogenesis. Advances in Neurology. 44: 465-73
Sellinger OZ, Gregor P, Sellinger A. (1985) Regional effects of the convulsant methionine sulfoximine on the benzodiazepine receptor complex of rat brain International Journal of Developmental Neuroscience. 3: 482
Sellinger OZ, Schatz RA, Porta R, et al. (1984) Brain methylation and epileptogenesis: the case of methionine sulfoximine. Annals of Neurology. 16: S115-20
Porta R, Schatz RA, Tatter SB, et al. (1983) Biosynthesis of polyamines in mouse brain: effects of methionine sulfoximine and adenosylhomocysteine. Journal of Neurochemistry. 40: 836-41
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