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Jack D. Keene

Affiliations: 
Duke University, Durham, NC 
Website:
http://mgm.duke.edu/faculty/keene/
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"Jack Keene"

Children

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Fen-Biao Gao grad student (Neurotree)
Charles C. Query grad student
Jeffrey Wilusz grad student
Craig C. Carson grad student 2000 Duke
Patrick J. Lager grad student 2006 Duke
Brian L. Bishop grad student 2007 Duke
April H. Spesock grad student 2009 Duke
Neelanjan Mukherjee grad student 2010 Duke
Matthew B. Friedersdorf grad student 2011 Duke
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Publications

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Ruthig VA, Hatkevich T, Hardy J, et al. (2023) The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation. Plos Genetics. 19: e1010656
Ruthig VA, Yokonishi T, Friedersdorf MB, et al. (2021) A transgenic DND1GFP fusion allele reports in vivo expression and RNA binding targets in undifferentiated mouse germ cells. Biology of Reproduction
Keene JD, Conte MR. (2020) Decision letter: Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation throughout mRNA lifespan with most impact on short tails Elife
Ruthig VA, Friedersdorf MB, Garness JA, et al. (2019) The RNA-binding protein DND1 acts Sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming. Development (Cambridge, England)
Bisogno LS, Friedersdorf MB, Keene JD. (2018) Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion. Iscience. 4: 97-108
Wang S, Jung Y, Hyun J, et al. (2018) RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 48: 1215-1229
Bisogno LS, Keene JD. (2018) RNA regulons in cancer and inflammation. Current Opinion in Genetics & Development. 48: 97-103
Bisogno LS, Keene JD. (2017) Analysis of post-transcriptional regulation during cancer progression using a donor-derived isogenic model of tumorigenesis. Methods (San Diego, Calif.)
Jung Y, Wang S, Friedersdorf M, et al. (2017) RNA-Binding Protein IGF2BP3 Regulates Cell Fate Decisions that Drive Cirrhosis Pathogenesis Gastroenterology. 152: S1073
Nicholson CO, Friedersdorf MB, Bisogno LS, et al. (2016) DO-RIP-seq to quantify RNA binding sites transcriptome-wide. Methods (San Diego, Calif.)
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