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Shannon D. Shields

Affiliations: 
Neuroscience Genentech, Inc., San Francisco, CA, United States 
Area:
Pain
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"Shannon Shields"
Mean distance: 13.92 (cluster 6)
 		SNBCP
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Parents

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Allan I. Basbaum grad student 1999-2007 UCSF
 (Anatomical and functional analysis of aquaporin I in the nociceptive and olfactory sensory systems.)
Stephen G. Waxman post-doc 2009-2014 Yale

Children

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Collaborators

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Sven-Eric Jordt collaborator 2001-2012
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Publications

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Deng L, Dourado M, Reese RM, et al. (2023) Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids. Neuron
Reese RM, Dourado M, Anderson K, et al. (2020) Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma. Scientific Reports. 10: 979
Shields SD, Deng L, Reese RM, et al. (2018) Insensitivity to pain upon adult-onset deletion of Na1.7 or its blockade with selective inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Chen H, Volgraf M, Do S, et al. (2018) Discovery of a Potent (4R,5S)-4-Fluoro-5-Methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist and its Methylene Phosphate Prodrug Guided By Molecular Modeling. Journal of Medicinal Chemistry
Shields SD, Butt RP, Dib-Hajj SD, et al. (2015) Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis. Plos One. 10: e0119067
González-Fernández C, Fernández-Martos CM, Shields SD, et al. (2014) Wnts are expressed in the spinal cord of adult mice and are differentially induced after injury. Journal of Neurotrauma. 31: 565-81
Shields SD, Cheng X, Uçeyler N, et al. (2012) Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10819-32
Shields SD, Ahn HS, Yang Y, et al. (2012) Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain. 153: 2017-30
Shields SD, Cheng X, Gasser A, et al. (2012) A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis. Annals of Neurology. 71: 186-94
Shields SD, Waxman SG. (2011) Cerebellar dysfunction in multiple sclerosis: in the blink of an eye. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 1152-4
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